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The header controls

The eye button and a small arrow beside it sit in the 3D Viewport header, to the left of Selectability & Visibility, next to the Gizmos and Overlays buttons. The eye turns the simulation on and off. The arrow opens a panel with the settings.

The eye button and its arrow in the 3D Viewport header

ControlWhat it does
Eye buttonTurns the simulation on and off. Shortcut: Shift+Alt+C. It turns red when the simulation is on but this viewport cannot show it.
KindDeuteranopia (red-green, the most common kind), Protanopia (red-green), Tritanopia (blue-yellow), Achromatopsia (no colour, only brightness).
StrengthHow much of the colour vision is gone. 1 is full, lower values show a milder form.
Split ViewThe picture as it is on the left, the simulation on the right.
PositionMoves the line between the two halves. Used while Split View is on.

The panel in Solid shading: the eye is red and a button offers Material Preview

  • The simulation shows only in Material Preview and Rendered. In Solid and Wireframe the eye turns red, and the panel has a button, Use Material Preview. DaltonPilot never changes your shading mode unless you click it.
  • Undo and Redo step through your changes to the simulation like any other change.